| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Citadel Advisors LLC | 9,158,677 | 9,158,677 | 87,044,066.21 | 0.0983 | 8.9051 | 04/07/2025 |
| 2 | Baker Bros. Advisors LP | 1,461,425 | 0 | 13,889,383.2 | 0.09 | 1.421 | 06/30/2025 |
| 3 | Adage Capital Management LP | 1,054,506 | 1,054,506 | 10,022,025.02 | 0.0163 | 1.0253 | 06/30/2025 |
| 4 | Octagon Capital Advisors LP | 1,018,021 | 1,018,021 | 9,675,271.58 | 1.4566 | 0.9898 | 06/30/2025 |
| 5 | Yiheng Capital Management LP | 656,309 | 0 | 6,237,560.74 | 1.4757 | 0.6381 | 06/30/2025 |
| 6 | Great Point Partners LLC | 374,679 | 374,679 | 3,560,949.22 | 1.1255 | 0.3643 | 06/30/2025 |
| 7 | Millennium Management LLC | 268,014 | 268,014 | 2,547,205.06 | 0.0022 | 0.2606 | 06/30/2025 |
| 8 | UBS Securities LLC | 164,200 | 1,824 | 1,560,556.8 | 0.0007 | 0.1597 | 06/30/2025 |
| 9 | Nan Fung Trinity (HK) Ltd. | 37,095 | 37,095 | 352,550.88 | 0.0402 | 0.0361 | 06/30/2025 |
| 10 | Citadel Securities LLC | 35,430 | 35,430 | 336,726.72 | 0.0011 | 0.0344 | 04/07/2025 |
| 11 | Myda Advisors LLC | 30,220 | 30,220 | 287,210.88 | 0.0767 | 0.0294 | 06/30/2025 |
| 12 | Morgan Stanley & Co. International Plc | 17,108 | -25,460 | 162,594.43 | 0.0017 | 0.0166 | 06/30/2025 |
| 13 | Point72 Asset Management LP | 17,000 | -269,250 | 161,568 | 0.0003 | 0.0165 | 06/30/2025 |
| 14 | Optiver US LLC | 8,347 | 8,311 | 79,329.89 | 0.002 | 0.0081 | 06/30/2025 |
| 15 | Barclays Bank Plc (Private Banking) | 6,611 | 6,313 | 62,830.94 | 0 | 0.0064 | 06/30/2025 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Fidelity Nasdaq Composite Index Fund | 3,877 | 0 | 36,847.01 | 0.0002 | 0.0038 | 06/30/2025 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Citadel Advisors LLC | 9,158,677 | 9,158,677 | 87,044,066.21 | 0.0983 | 8.9051 | 04/07/2025 |
| 2 | Adage Capital Management LP | 1,054,506 | 1,054,506 | 10,022,025.02 | 0.0163 | 1.0253 | 06/30/2025 |
| 3 | Octagon Capital Advisors LP | 1,018,021 | 1,018,021 | 9,675,271.58 | 1.4566 | 0.9898 | 06/30/2025 |
| 4 | Great Point Partners LLC | 374,679 | 374,679 | 3,560,949.22 | 1.1255 | 0.3643 | 06/30/2025 |
| 5 | Millennium Management LLC | 268,014 | 268,014 | 2,547,205.06 | 0.0022 | 0.2606 | 06/30/2025 |
| 6 | Nan Fung Trinity (HK) Ltd. | 37,095 | 37,095 | 352,550.88 | 0.0402 | 0.0361 | 06/30/2025 |
| 7 | Citadel Securities LLC | 35,430 | 35,430 | 336,726.72 | 0.0011 | 0.0344 | 04/07/2025 |
| 8 | Myda Advisors LLC | 30,220 | 30,220 | 287,210.88 | 0.0767 | 0.0294 | 06/30/2025 |
| 9 | Optiver US LLC | 8,347 | 8,311 | 79,329.89 | 0.002 | 0.0081 | 06/30/2025 |
| 10 | Barclays Bank Plc (Private Banking) | 6,611 | 6,313 | 62,830.94 | 0 | 0.0064 | 06/30/2025 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Braidwell LP | 0 | -2,393,815 | 0 | 0 | 0 | |
| 2 | Point72 Asset Management LP | 17,000 | -269,250 | 161,568 | 0.0003 | 0.0165 | 06/30/2025 |
| 3 | Boxer Capital Management LLC | 0 | -50,000 | 0 | 0 | 0 | |
| 4 | Morgan Stanley & Co. International Plc | 17,108 | -25,460 | 162,594.43 | 0.0017 | 0.0166 | 06/30/2025 |
| 5 | Morgan Stanley Smith Barney LLC (Investment Management) | 366 | -2,787 | 3,478.46 | 0 | 0.0004 | 06/30/2025 |
| 6 | BNP Paribas Financial Markets | 0 | -1,650 | 0 | 0 | 0 | |
| 7 | Bank of America, NA (Private Banking) | 0 | -123 | 0 | 0 | 0 |
Data provided by FactSet Research Systems Inc.