| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Soleus Capital Management LP (Investment Management) | 7,309,254 | 0 | 10,013,677.98 | 0.5907 | 19.6995 | 06/30/2025 |
| 2 | Morgan Stanley & Co. International Plc | 3,362,580 | -3,910 | 4,606,734.6 | 0.049 | 9.0626 | 06/30/2025 |
| 3 | Rock Springs Capital Management LP | 1,270,000 | -321,800 | 1,739,900 | 0.1007 | 3.4228 | 06/30/2025 |
| 4 | Bruce & Co., Inc. | 553,652 | 0 | 758,503.24 | 0.2351 | 1.4922 | 06/30/2025 |
| 5 | Apis Capital Advisors LLC | 226,288 | -292,712 | 310,014.56 | 0.0979 | 0.6099 | 06/30/2025 |
| 6 | UBS Securities LLC | 174,674 | 129,526 | 239,303.38 | 0.0001 | 0.4708 | 06/30/2025 |
| 7 | Schonfeld Strategic Advisors LLC | 172,136 | 11,336 | 235,826.32 | 0.0017 | 0.4639 | 06/30/2025 |
| 8 | Parkman Healthcare Partners LLC | 154,832 | 0 | 212,119.84 | 0.0224 | 0.4173 | 06/30/2025 |
| 9 | Cahill Financial Advisors, Inc. | 134,960 | 0 | 184,895.2 | 0.0222 | 0.3637 | 06/30/2025 |
| 10 | Summit Trail Advisors LLC | 102,339 | 102,339 | 140,204.43 | 0.0023 | 0.2758 | 06/30/2025 |
| 11 | Sage Mountain Advisors LLC | 100,000 | 100,000 | 137,000 | 0.0087 | 0.2695 | 06/30/2025 |
| 12 | Cetera Investment Advisers LLC | 75,000 | 19,000 | 102,750 | 0.0002 | 0.2021 | 06/30/2025 |
| 13 | Commonwealth Equity Services LLC | 69,160 | 0 | 94,749.2 | 0.0001 | 0.1864 | 06/30/2025 |
| 14 | Citadel Securities LLC | 50,621 | -14,621 | 69,350.77 | 0.0002 | 0.1364 | 06/30/2025 |
| 15 | Orion Capital Management LLC (CA) | 38,000 | 0 | 52,060 | 0.0192 | 0.1024 | 06/30/2025 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Bruce Fund | 529,794 | 0 | 725,817.78 | 0.213 | 1.4279 | 06/30/2025 |
| 2 | PSM Growth UI | 80,000 | 80,000 | 109,600 | 1.7222 | 0.2156 | 05/30/2025 |
| 3 | Fidelity Nasdaq Composite Index Fund | 22,764 | 0 | 31,186.68 | 0.0002 | 0.0614 | 06/30/2025 |
| 4 | LUX IM - Global Medtech | 7,741 | 0 | 10,605.17 | 0.0062 | 0.0209 | 12/31/2024 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | UBS Securities LLC | 174,674 | 129,526 | 239,303.38 | 0.0001 | 0.4708 | 06/30/2025 |
| 2 | Summit Trail Advisors LLC | 102,339 | 102,339 | 140,204.43 | 0.0023 | 0.2758 | 06/30/2025 |
| 3 | Sage Mountain Advisors LLC | 100,000 | 100,000 | 137,000 | 0.0087 | 0.2695 | 06/30/2025 |
| 4 | Simplicity Wealth LLC | 32,548 | 32,548 | 44,590.76 | 0.0018 | 0.0877 | 06/30/2025 |
| 5 | Cetera Investment Advisers LLC | 75,000 | 19,000 | 102,750 | 0.0002 | 0.2021 | 06/30/2025 |
| 6 | Bernard Caroli Wealth Management, Inc. | 13,000 | 13,000 | 17,810 | 0.0066 | 0.035 | 06/30/2025 |
| 7 | Virtu Americas LLC | 11,914 | 11,914 | 16,322.18 | 0.0008 | 0.0321 | 06/30/2025 |
| 8 | Schonfeld Strategic Advisors LLC | 172,136 | 11,336 | 235,826.32 | 0.0017 | 0.4639 | 06/30/2025 |
| 9 | CIBC Private Wealth Advisors, Inc. | 10,000 | 10,000 | 13,700 | 0 | 0.027 | 06/30/2025 |
| 10 | Citigroup Global Markets, Inc. (Investment Management) | 5,548 | 5,548 | 7,600.76 | 0 | 0.015 | 06/30/2025 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Archon Capital Management LLC | 0 | -982,681 | 0 | 0 | 0 | |
| 2 | Rock Springs Capital Management LP | 1,270,000 | -321,800 | 1,739,900 | 0.1007 | 3.4228 | 06/30/2025 |
| 3 | Apis Capital Advisors LLC | 226,288 | -292,712 | 310,014.56 | 0.0979 | 0.6099 | 06/30/2025 |
| 4 | Millennium Management LLC | 0 | -48,915 | 0 | 0 | 0 | |
| 5 | Jane Street Capital LLC | 0 | -31,361 | 0 | 0 | 0 | |
| 6 | BNP Paribas Financial Markets | 26,105 | -22,545 | 35,763.85 | 0 | 0.0704 | 06/30/2025 |
| 7 | Illumine Investment Management LLC | 0 | -22,400 | 0 | 0 | 0 | |
| 8 | Redhawk Wealth Advisors, Inc. | 0 | -17,500 | 0 | 0 | 0 | |
| 9 | Citadel Securities LLC | 50,621 | -14,621 | 69,350.77 | 0.0002 | 0.1364 | 06/30/2025 |
| 10 | Morgan Stanley & Co. International Plc | 3,362,580 | -3,910 | 4,606,734.6 | 0.049 | 9.0626 | 06/30/2025 |
Data provided by FactSet Research Systems Inc.