| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | BlackRock Fund Advisors | 498,996 | -85,295 | 7,949,006.28 | 0.0002 | 0.3927 | 06/30/2025 |
| 2 | Goldman Sachs & Co. LLC (Private Banking) | 415,465 | 415,465 | 6,618,357.45 | 0.0028 | 0.327 | 06/30/2025 |
| 3 | Morgan Stanley & Co. International Plc | 313,522 | 150,022 | 4,994,405.46 | 0.054 | 0.2468 | 06/30/2025 |
| 4 | Susquehanna Financial Group LLLP | 234,587 | 80,608 | 3,736,970.91 | 0.0056 | 0.1846 | 06/30/2025 |
| 5 | Summit X LLC | 199,295 | 53,640 | 3,174,769.35 | 0.5681 | 0.1569 | 06/30/2025 |
| 6 | Morgan Stanley & Co. LLC | 179,435 | -45,818 | 2,858,399.55 | 0.001 | 0.1412 | 06/30/2025 |
| 7 | UBS Securities LLC | 160,038 | -5,115 | 2,549,405.34 | 0.0011 | 0.126 | 06/30/2025 |
| 8 | Aperio Group LLC | 135,167 | 7,576 | 2,153,210.31 | 0.0018 | 0.1064 | 06/30/2025 |
| 9 | Group One Trading LLC | 90,902 | 90,902 | 1,448,068.86 | 0.0448 | 0.0715 | 06/30/2025 |
| 10 | Penbrook Management LLC | 87,675 | -3,400 | 1,396,662.75 | 1.046 | 0.069 | 06/30/2025 |
| 11 | RBC Dominion Securities, Inc. (Investment Management) | 85,400 | 85,400 | 1,360,422 | 0.001 | 0.0672 | 06/30/2025 |
| 12 | Citadel Securities LLC | 74,636 | 74,636 | 1,188,951.48 | 0.0039 | 0.0587 | 06/30/2025 |
| 13 | Prosperity Wealth Management, Inc. | 50,100 | -43,145 | 798,093 | 0.2854 | 0.0394 | 06/30/2025 |
| 14 | LPL Financial LLC | 50,047 | 11,165 | 797,248.71 | 0.0003 | 0.0394 | 06/30/2025 |
| 15 | Rockbridge Investment Management LLC | 49,150 | 0 | 782,959.5 | 0.0819 | 0.0387 | 06/30/2025 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | iShares Biotechnology ETF | 494,215 | -74,424 | 7,872,844.95 | 0.1401 | 0.389 | 07/31/2025 |
| 2 | iShares IV Plc - NASDAQ US Biotechnology UCITS ETF | 26,775 | 11,303 | 426,525.75 | 0.0728 | 0.0211 | 07/31/2025 |
| 3 | Fidelity Nasdaq Composite Index Fund | 18,245 | 0 | 290,642.85 | 0.0014 | 0.0144 | 06/30/2025 |
| 4 | Invesco Markets Plc - NASDAQ Biotech UCITS ETF | 13,313 | 4,020 | 212,076.09 | 0.0736 | 0.0105 | 07/31/2025 |
| 5 | China Universal Nasdaq Biotechnology Index ETF | 6,776 | 0 | 107,941.68 | 0.048 | 0.0053 | 12/31/2024 |
| 6 | ActivePassive International Equity ETF | 4,970 | -3,497 | 79,172.1 | 0.009 | 0.0039 | 07/31/2025 |
| 7 | Mirae Asset Tiger NASDAQ Bio ETF | 2,107 | 930 | 33,564.51 | 0.0757 | 0.0017 | 07/31/2025 |
| 8 | ProShares Ultra NASDAQ Biotechnology | 1,673 | 190 | 26,650.89 | 0.0547 | 0.0013 | 07/31/2025 |
| 9 | Invesco Nasdaq Biotechnology ETF | 1,617 | 400 | 25,758.81 | 0.0724 | 0.0013 | 07/31/2025 |
| 10 | Xtrackers IE Plc - MSCI Genomic Healthcare Innov UCITS ETF | 1,552 | 1,552 | 24,723.36 | 0.3804 | 0.0012 | 07/31/2025 |
| 11 | DFA International Core Equity 2 Portfolio | 796 | 0 | 12,680.28 | 0 | 0.0006 | 04/30/2025 |
| 12 | GF Nasdaq Biotechnology Index Fund | 671 | 0 | 10,689.03 | 0.0412 | 0.0005 | 12/31/2024 |
| 13 | Capital Nasdaq Biotechnology Index ETF | 135 | 0 | 2,150.55 | 0.0263 | 0.0001 | 07/31/2025 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Goldman Sachs & Co. LLC (Private Banking) | 415,465 | 415,465 | 6,618,357.45 | 0.0028 | 0.327 | 06/30/2025 |
| 2 | Morgan Stanley & Co. International Plc | 313,522 | 150,022 | 4,994,405.46 | 0.054 | 0.2468 | 06/30/2025 |
| 3 | Group One Trading LLC | 90,902 | 90,902 | 1,448,068.86 | 0.0448 | 0.0715 | 06/30/2025 |
| 4 | RBC Dominion Securities, Inc. (Investment Management) | 85,400 | 85,400 | 1,360,422 | 0.001 | 0.0672 | 06/30/2025 |
| 5 | Susquehanna Financial Group LLLP | 234,587 | 80,608 | 3,736,970.91 | 0.0056 | 0.1846 | 06/30/2025 |
| 6 | Citadel Securities LLC | 74,636 | 74,636 | 1,188,951.48 | 0.0039 | 0.0587 | 06/30/2025 |
| 7 | Summit X LLC | 199,295 | 53,640 | 3,174,769.35 | 0.5681 | 0.1569 | 06/30/2025 |
| 8 | Marshall Wace LLP | 40,710 | 40,710 | 648,510.3 | 0.0007 | 0.032 | 06/30/2025 |
| 9 | Two Sigma Investments LP | 33,213 | 33,213 | 529,083.09 | 0.0009 | 0.0261 | 06/30/2025 |
| 10 | Millennium Management LLC | 32,283 | 32,283 | 514,268.19 | 0.0004 | 0.0254 | 06/30/2025 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Merrill Lynch International (Investment Management) | 0 | -200,000 | 0 | 0 | 0 | |
| 2 | Oaktree Capital Management LP | 0 | -179,593 | 0 | 0 | 0 | |
| 3 | Jane Street Capital LLC | 0 | -102,175 | 0 | 0 | 0 | |
| 4 | BlackRock Fund Advisors | 498,996 | -85,295 | 7,949,006.28 | 0.0002 | 0.3927 | 06/30/2025 |
| 5 | Citigroup Global Markets, Inc. (Investment Management) | 25,866 | -74,134 | 412,045.38 | 0.0003 | 0.0204 | 06/30/2025 |
| 6 | BofA Securities, Inc. | 6,563 | -64,437 | 104,548.59 | 0.0002 | 0.0052 | 06/30/2025 |
| 7 | Oaktree Fund Advisors LLC | 0 | -47,909 | 0 | 0 | 0 | |
| 8 | Morgan Stanley & Co. LLC | 179,435 | -45,818 | 2,858,399.55 | 0.001 | 0.1412 | 06/30/2025 |
| 9 | Prosperity Wealth Management, Inc. | 50,100 | -43,145 | 798,093 | 0.2854 | 0.0394 | 06/30/2025 |
| 10 | Cubist Systematic Strategies LLC | 12,204 | -22,987 | 194,409.72 | 0.002 | 0.0096 | 06/30/2025 |
Data provided by FactSet Research Systems Inc.