| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Cormorant Asset Management LP | 3,978,229 | 1,080,372 | 62,139,936.98 | 4.1038 | 5.4601 | 06/30/2026 |
| 2 | Balyasny Asset Management LP | 3,061,668 | 2,183,822 | 47,823,254.16 | 0.0907 | 4.2022 | 06/30/2026 |
| 3 | Point72 Asset Management LP | 2,140,664 | 2,140,664 | 33,437,171.68 | 0.0524 | 2.9381 | 06/30/2026 |
| 4 | Perceptive Advisors LLC | 1,793,190 | 1,793,190 | 28,009,627.8 | 0.4884 | 2.4612 | 06/30/2026 |
| 5 | Casdin Capital LLC | 1,250,000 | 711,539 | 19,525,000 | 0.9489 | 1.7156 | 06/30/2026 |
| 6 | Adar1 Capital Management LLC | 1,017,805 | 899,896 | 15,898,114.1 | 0.8016 | 1.3969 | 06/30/2026 |
| 7 | Octagon Capital Advisors LP | 934,716 | 934,716 | 14,600,263.92 | 1.8311 | 1.2829 | 06/30/2026 |
| 8 | Millennium Management LLC | 807,832 | 126,057 | 12,618,335.84 | 0.0086 | 1.1088 | 06/30/2026 |
| 9 | Braidwell LP | 795,214 | 795,214 | 12,421,242.68 | 0.4363 | 1.0914 | 06/30/2026 |
| 10 | Squadron Capital Management LLC | 764,876 | -500,355 | 11,947,363.12 | 4.747 | 1.0498 | 06/30/2026 |
| 11 | Eventide Asset Management LLC | 718,747 | 718,747 | 11,226,828.14 | 0.1602 | 0.9865 | 06/30/2026 |
| 12 | Superstring Capital Management LP | 552,501 | 137,649 | 8,630,065.62 | 5.1212 | 0.7583 | 06/30/2026 |
| 13 | Adage Capital Management LP | 538,461 | 0 | 8,410,760.82 | 0.0115 | 0.739 | 06/30/2026 |
| 14 | Woodline Partners LP | 455,733 | 246,474 | 7,118,549.46 | 0.022 | 0.6255 | 06/30/2026 |
| 15 | Soleus Capital Management LP (Investment Management) | 405,523 | 405,523 | 6,334,269.26 | 0.2373 | 0.5566 | 06/30/2026 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Eventide Healthcare & Life Sciences Fund | 718,747 | 718,747 | 11,226,828.14 | 0.6958 | 0.9865 | 06/30/2026 |
| 2 | Tema Oncology ETF | 75,283 | 9,249 | 1,175,920.46 | 0.5807 | 0.1033 | 09/30/2026 |
| 3 | Virtus Biotech Clinical Trials ETF | 30,749 | 30,749 | 480,299.38 | 1.1453 | 0.0422 | 09/30/2026 |
| 4 | State Street SPDR S&P Emerging Markets Small Cap ETF | 29,000 | 29,000 | 452,980 | 0.0675 | 0.0398 | 09/30/2026 |
| 5 | Fidelity Nasdaq Composite Index Fund | 17,020 | 5,887 | 265,852.4 | 0.0009 | 0.0234 | 08/31/2026 |
| 6 | State Street SPDR S&P China ETF | 7,200 | 7,200 | 112,464 | 0.0249 | 0.0099 | 09/30/2026 |
| 7 | BlackRock Strategic Fds. - Asia Pacific Div. Eq. Abs. Return | 1,728 | 1,728 | 26,991.36 | 0.0154 | 0.0024 | 07/31/2026 |
| 8 | ProFunds - UltraChina | 1,156 | 1,156 | 18,056.72 | 0.0965 | 0.0016 | 07/31/2026 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Balyasny Asset Management LP | 3,061,668 | 2,183,822 | 47,823,254.16 | 0.0907 | 4.2022 | 06/30/2026 |
| 2 | Point72 Asset Management LP | 2,140,664 | 2,140,664 | 33,437,171.68 | 0.0524 | 2.9381 | 06/30/2026 |
| 3 | Perceptive Advisors LLC | 1,793,190 | 1,793,190 | 28,009,627.8 | 0.4884 | 2.4612 | 06/30/2026 |
| 4 | Cormorant Asset Management LP | 3,978,229 | 1,080,372 | 62,139,936.98 | 4.1038 | 5.4601 | 06/30/2026 |
| 5 | Octagon Capital Advisors LP | 934,716 | 934,716 | 14,600,263.92 | 1.8311 | 1.2829 | 06/30/2026 |
| 6 | Adar1 Capital Management LLC | 1,017,805 | 899,896 | 15,898,114.1 | 0.8016 | 1.3969 | 06/30/2026 |
| 7 | Braidwell LP | 795,214 | 795,214 | 12,421,242.68 | 0.4363 | 1.0914 | 06/30/2026 |
| 8 | Eventide Asset Management LLC | 718,747 | 718,747 | 11,226,828.14 | 0.1602 | 0.9865 | 06/30/2026 |
| 9 | Casdin Capital LLC | 1,250,000 | 711,539 | 19,525,000 | 0.9489 | 1.7156 | 06/30/2026 |
| 10 | Soleus Capital Management LP (Investment Management) | 405,523 | 405,523 | 6,334,269.26 | 0.2373 | 0.5566 | 06/30/2026 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Squadron Capital Management LLC | 764,876 | -500,355 | 11,947,363.12 | 4.747 | 1.0498 | 06/30/2026 |
| 2 | T. Rowe Price Associates, Inc. (IM) | 0 | -99,843 | 0 | 0 | 0 | |
| 3 | UBS Securities LLC | 52,895 | -69,366 | 826,219.9 | 0.0003 | 0.0726 | 06/30/2026 |
| 4 | Cantor Fitzgerald & Co. | 0 | -40,310 | 0 | 0 | 0 | |
| 5 | TD Asset Management, Inc. | 0 | -35,746 | 0 | 0 | 0 | |
| 6 | Persistent Asset Partners Ltd. | 0 | -33,732 | 0 | 0 | 0 | |
| 7 | Columbia Management Investment Advisers LLC | 86,700 | -33,456 | 1,354,254 | 0.0003 | 0.119 | 06/30/2026 |
| 8 | Tidal Investments LLC | 44,354 | -21,680 | 692,809.48 | 0.0016 | 0.0609 | 06/30/2026 |
| 9 | Dymon Asia Capital (Singapore) Pte Ltd. | 0 | -15,000 | 0 | 0 | 0 | |
| 10 | Affinity Asset Advisors LLC | 153,847 | -10,901 | 2,403,090.14 | 0.1392 | 0.2112 | 06/30/2026 |
Data provided by FactSet Research Systems Inc.