| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Fidelity Management & Research Co. LLC | 4,872,036 | 165,127 | 4,019,575,861.08 | 0.1903 | 7.7877 | 06/30/2026 |
| 2 | Janus Henderson Investors US LLC | 2,415,238 | -78,584 | 1,992,643,807.14 | 0.8768 | 3.8606 | 06/30/2026 |
| 3 | Capital Research & Management Co. (World Investors) | 2,199,770 | -56,446 | 1,814,876,243.1 | 0.1613 | 3.5162 | 06/30/2026 |
| 4 | T. Rowe Price Associates, Inc. (IM) | 1,959,784 | -617,598 | 1,616,880,593.52 | 0.1743 | 3.1326 | 06/30/2026 |
| 5 | Artisan Partners LP | 1,508,778 | 40,796 | 1,244,787,113.34 | 1.0176 | 2.4117 | 06/30/2026 |
| 6 | Avoro Capital Advisor LLC | 1,000,000 | 0 | 825,030,000 | 8.7089 | 1.5984 | 06/30/2026 |
| 7 | T. Rowe Price International Ltd. | 718,263 | -79,310 | 592,588,522.89 | 0.3122 | 1.1481 | 06/30/2026 |
| 8 | RTW Investments LP | 709,446 | 0 | 585,314,233.38 | 5.3963 | 1.134 | 06/30/2026 |
| 9 | Wellington Management Co. LLP | 666,317 | -71,302 | 549,731,514.51 | 0.0882 | 1.0651 | 06/30/2026 |
| 10 | Invesco Advisers, Inc. | 422,199 | -137,911 | 348,326,840.97 | 0.1366 | 0.6749 | 06/30/2026 |
| 11 | AllianceBernstein LP | 395,661 | -26,643 | 326,432,194.83 | 0.0926 | 0.6324 | 06/30/2026 |
| 12 | BlackRock Fund Advisors | 371,986 | 28,775 | 306,899,609.58 | 0.0056 | 0.5946 | 06/30/2026 |
| 13 | Bellevue Asset Management AG | 301,000 | -12,000 | 248,334,030 | 4.346 | 0.4811 | 06/30/2026 |
| 14 | Sands Capital Management LLC | 298,599 | -41,686 | 246,353,132.97 | 0.6076 | 0.4773 | 06/30/2026 |
| 15 | Bessemer Investment Management LLC | 267,779 | 203,528 | 220,925,708.37 | 0.2578 | 0.428 | 06/30/2026 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | American Funds EUPAC Fund | 1,024,240 | -72,961 | 845,028,727.2 | 0.6349 | 1.6372 | 06/30/2026 |
| 2 | Fidelity Growth Company Commingled Pool | 817,584 | 1,112 | 674,531,327.52 | 0.5007 | 1.3069 | 08/31/2026 |
| 3 | American Funds New Economy Fund | 729,820 | 16,126 | 602,123,394.6 | 1.2386 | 1.1666 | 06/30/2026 |
| 4 | Fidelity Growth Company Fund | 608,314 | -752 | 501,877,299.42 | 0.4903 | 0.9724 | 08/31/2026 |
| 5 | Janus Henderson Forty Fund | 518,956 | -18,917 | 428,154,268.68 | 1.7206 | 0.8295 | 06/30/2026 |
| 6 | Fidelity OTC Portfolio | 472,226 | -12,600 | 389,600,616.78 | 0.8051 | 0.7548 | 08/31/2026 |
| 7 | iShares Biotechnology ETF | 436,887 | 95,004 | 360,444,881.61 | 3.284 | 0.6983 | 09/30/2026 |
| 8 | St. James's Place Global Growth Unit Trust | 309,191 | 0 | 255,091,850.73 | 1.0711 | 0.4942 | 01/31/2026 |
| 9 | Janus Henderson Enterprise Fund | 309,064 | 0 | 254,987,071.92 | 1.204 | 0.494 | 06/30/2026 |
| 10 | Fidelity Contrafund | 240,515 | 43,785 | 198,432,090.45 | 0.1084 | 0.3844 | 08/31/2026 |
| 11 | T Rowe Price Growth Stock Fund | 225,019 | -46,539 | 185,647,425.57 | 0.3581 | 0.3597 | 06/30/2026 |
| 12 | T. Rowe Price Large Cap Growth Fund | 211,419 | -875 | 174,427,017.57 | 0.8029 | 0.3379 | 06/30/2026 |
| 13 | T. Rowe Price New Horizons Fund | 208,186 | -8,097 | 171,759,695.58 | 1.3013 | 0.3328 | 06/30/2026 |
| 14 | T Rowe Price Overseas Stock Fund | 194,314 | -40,835 | 160,314,879.42 | 0.6541 | 0.3106 | 06/30/2026 |
| 15 | Fidelity Puritan Fund | 182,989 | -43,200 | 150,971,414.67 | 0.6415 | 0.2925 | 08/31/2026 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Bessemer Investment Management LLC | 267,779 | 203,528 | 220,925,708.37 | 0.2578 | 0.428 | 06/30/2026 |
| 2 | Fidelity Management & Research Co. LLC | 4,872,036 | 165,127 | 4,019,575,861.08 | 0.1903 | 7.7877 | 06/30/2026 |
| 3 | Barclays Bank Plc (Private Banking) | 134,427 | 129,152 | 110,906,307.81 | 0.0589 | 0.2149 | 06/30/2026 |
| 4 | Capital Research & Management Co. (Global Investors) | 88,511 | 88,511 | 73,024,230.33 | 0.0091 | 0.1415 | 06/30/2026 |
| 5 | Bank of America, NA (Private Banking) | 116,549 | 80,615 | 96,156,421.47 | 0.0246 | 0.1863 | 06/30/2026 |
| 6 | Two Sigma Investments LP | 185,638 | 76,517 | 153,156,919.14 | 0.1163 | 0.2967 | 06/30/2026 |
| 7 | 1832 Asset Management LP | 157,940 | 73,740 | 130,305,238.2 | 0.1098 | 0.2525 | 06/30/2026 |
| 8 | Canada Pension Plan Investment Board | 60,577 | 60,577 | 49,977,842.31 | 0.0189 | 0.0968 | 06/30/2026 |
| 9 | Westfield Capital Management Co. LP | 57,082 | 57,082 | 47,094,362.46 | 0.1593 | 0.0912 | 06/30/2026 |
| 10 | Morgan Stanley & Co. LLC | 160,006 | 57,037 | 132,009,750.18 | 0.0383 | 0.2558 | 06/30/2026 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | T. Rowe Price Associates, Inc. (IM) | 1,959,784 | -617,598 | 1,616,880,593.52 | 0.1743 | 3.1326 | 06/30/2026 |
| 2 | Invesco Advisers, Inc. | 422,199 | -137,911 | 348,326,840.97 | 0.1366 | 0.6749 | 06/30/2026 |
| 3 | T. Rowe Price International Ltd. | 718,263 | -79,310 | 592,588,522.89 | 0.3122 | 1.1481 | 06/30/2026 |
| 4 | Janus Henderson Investors US LLC | 2,415,238 | -78,584 | 1,992,643,807.14 | 0.8768 | 3.8606 | 06/30/2026 |
| 5 | Wellington Management Co. LLP | 666,317 | -71,302 | 549,731,514.51 | 0.0882 | 1.0651 | 06/30/2026 |
| 6 | Fiera Capital Corp. (Investment Management) | 26,546 | -70,955 | 21,901,246.38 | 0.0799 | 0.0424 | 06/30/2026 |
| 7 | Braidwell LP | 17,707 | -67,232 | 14,608,806.21 | 0.5132 | 0.0283 | 06/30/2026 |
| 8 | Goldman Sachs & Co. LLC (Private Banking) | 53,512 | -58,906 | 44,149,005.36 | 0.0112 | 0.0855 | 06/30/2026 |
| 9 | Capital Research & Management Co. (World Investors) | 2,199,770 | -56,446 | 1,814,876,243.1 | 0.1613 | 3.5162 | 06/30/2026 |
| 10 | TD Asset Management, Inc. | 24,675 | -56,149 | 20,357,615.25 | 0.0095 | 0.0394 | 06/30/2026 |
Data provided by FactSet Research Systems Inc.