| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Fidelity Management & Research Co. LLC | 4,706,909 | -585,974 | 4,154,129,607.04 | 0.2159 | 7.6061 | 03/31/2026 |
| 2 | Janus Henderson Investors US LLC | 2,493,822 | 71,412 | 2,200,947,544.32 | 0.9949 | 4.0299 | 03/31/2026 |
| 3 | T. Rowe Price Associates, Inc. (IM) | 2,259,352 | -411,893 | 1,994,013,701.12 | 0.2274 | 3.651 | 04/24/2026 |
| 4 | Capital Research & Management Co. (World Investors) | 2,256,216 | 339,982 | 1,991,245,992.96 | 0.1836 | 3.6459 | 03/31/2026 |
| 5 | Artisan Partners LP | 1,467,982 | -288,960 | 1,295,582,193.92 | 0.9557 | 2.3722 | 03/31/2026 |
| 6 | Avoro Capital Advisor LLC | 1,000,000 | 10,000 | 882,560,000 | 8.5833 | 1.6159 | 03/31/2026 |
| 7 | T. Rowe Price International Ltd. | 797,985 | 106,906 | 704,269,641.6 | 0.4029 | 1.2895 | 04/24/2026 |
| 8 | Wellington Management Co. LLP | 737,619 | 265,910 | 650,993,024.64 | 0.1043 | 1.1919 | 03/31/2026 |
| 9 | RTW Investments LP | 709,446 | 35,949 | 626,128,661.76 | 5.4491 | 1.1464 | 03/31/2026 |
| 10 | Invesco Advisers, Inc. | 560,110 | 172,663 | 494,330,681.6 | 0.201 | 0.9051 | 03/31/2026 |
| 11 | AllianceBernstein LP | 422,304 | 8,122 | 372,708,618.24 | 0.1072 | 0.6824 | 03/31/2026 |
| 12 | BlackRock Fund Advisors | 343,211 | 46,948 | 302,904,300.16 | 0.0059 | 0.5546 | 03/31/2026 |
| 13 | Sands Capital Management LLC | 340,285 | -16,585 | 300,321,929.6 | 0.7326 | 0.5499 | 03/31/2026 |
| 14 | Bellevue Asset Management AG | 313,000 | -146,839 | 276,241,280 | 4.6562 | 0.5058 | 03/31/2026 |
| 15 | SEI Investments Management Corp. | 286,966 | -43,540 | 253,264,712.96 | 0.1914 | 0.4637 | 03/31/2026 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | American Funds EUPAC Fund | 1,024,240 | -61,630 | 903,953,254.4 | 0.7004 | 1.6551 | 06/30/2026 |
| 2 | Fidelity Growth Company Commingled Pool | 817,584 | -3,581 | 721,566,935.04 | 0.6167 | 1.3212 | 05/31/2026 |
| 3 | American Funds New Economy Fund | 729,820 | 298,129 | 644,109,939.2 | 1.4289 | 1.1793 | 06/30/2026 |
| 4 | Fidelity Growth Company Fund | 609,066 | 0 | 537,537,288.96 | 0.6027 | 0.9842 | 05/31/2026 |
| 5 | Janus Henderson Forty Fund | 537,873 | 0 | 474,705,194.88 | 2.0352 | 0.8692 | 03/31/2026 |
| 6 | Fidelity OTC Portfolio | 474,426 | -67,000 | 418,709,410.56 | 1.0544 | 0.7666 | 05/31/2026 |
| 7 | iShares Biotechnology ETF | 368,177 | 69,827 | 324,938,293.12 | 3.6022 | 0.595 | 06/30/2026 |
| 8 | St. James's Place Global Growth Unit Trust | 309,191 | 35,005 | 272,879,608.96 | 1.1824 | 0.4996 | 01/31/2026 |
| 9 | Janus Henderson Enterprise Fund | 309,064 | -14,387 | 272,767,523.84 | 1.1747 | 0.4994 | 03/31/2026 |
| 10 | Invesco American Franchise Fund | 245,620 | 20,954 | 216,774,387.2 | 1.3013 | 0.3969 | 05/31/2026 |
| 11 | T Rowe Price Growth Stock Fund | 225,019 | -25,061 | 198,592,768.64 | 0.4214 | 0.3636 | 06/30/2026 |
| 12 | T. Rowe Price Large Cap Growth Fund | 211,419 | -4,754 | 186,589,952.64 | 0.938 | 0.3416 | 06/30/2026 |
| 13 | Fidelity Puritan Fund | 209,689 | -41,400 | 185,063,123.84 | 0.798 | 0.3388 | 05/31/2026 |
| 14 | T. Rowe Price New Horizons Fund | 208,186 | -24,241 | 183,736,636.16 | 1.3923 | 0.3364 | 06/30/2026 |
| 15 | T Rowe Price Overseas Stock Fund | 194,314 | 2,687 | 171,493,763.84 | 0.6951 | 0.314 | 06/30/2026 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Capital Research & Management Co. (World Investors) | 2,256,216 | 339,982 | 1,991,245,992.96 | 0.1836 | 3.6459 | 03/31/2026 |
| 2 | Wellington Management Co. LLP | 737,619 | 265,910 | 650,993,024.64 | 0.1043 | 1.1919 | 03/31/2026 |
| 3 | Invesco Advisers, Inc. | 560,110 | 172,663 | 494,330,681.6 | 0.201 | 0.9051 | 03/31/2026 |
| 4 | BNP Paribas Financial Markets SNC | 177,836 | 107,092 | 156,950,940.16 | 0.0882 | 0.2874 | 03/31/2026 |
| 5 | T. Rowe Price International Ltd. | 797,985 | 106,906 | 704,269,641.6 | 0.4029 | 1.2895 | 04/24/2026 |
| 6 | Adage Capital Management LP | 90,000 | 90,000 | 79,430,400 | 0.1101 | 0.1454 | 03/31/2026 |
| 7 | Capfi Delen Asset Management NV | 87,188 | 87,188 | 76,948,641.28 | 0.2925 | 0.1409 | 04/30/2026 |
| 8 | BMO Asset Management, Inc. | 77,875 | 76,211 | 68,729,360 | 0.0339 | 0.1258 | 03/31/2026 |
| 9 | Janus Henderson Investors US LLC | 2,493,822 | 71,412 | 2,200,947,544.32 | 0.9949 | 4.0299 | 03/31/2026 |
| 10 | Goldman Sachs & Co. LLC (Private Banking) | 112,418 | 68,914 | 99,215,630.08 | 0.0315 | 0.1817 | 03/31/2026 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Fidelity Management & Research Co. LLC | 4,706,909 | -585,974 | 4,154,129,607.04 | 0.2159 | 7.6061 | 03/31/2026 |
| 2 | T. Rowe Price Associates, Inc. (IM) | 2,259,352 | -411,893 | 1,994,013,701.12 | 0.2274 | 3.651 | 04/24/2026 |
| 3 | Artisan Partners LP | 1,467,982 | -288,960 | 1,295,582,193.92 | 0.9557 | 2.3722 | 03/31/2026 |
| 4 | ClearBridge Investments LLC | 231,356 | -282,408 | 204,185,551.36 | 0.1591 | 0.3739 | 03/31/2026 |
| 5 | Voya Investment Management Co. LLC | 5,545 | -163,553 | 4,893,795.2 | 0.004 | 0.009 | 03/31/2026 |
| 6 | Two Sigma Investments LP | 109,121 | -149,435 | 96,305,829.76 | 0.0725 | 0.1763 | 03/31/2026 |
| 7 | Bellevue Asset Management AG | 313,000 | -146,839 | 276,241,280 | 4.6562 | 0.5058 | 03/31/2026 |
| 8 | Two Sigma Advisers LP | 0 | -135,500 | 0 | 0 | 0 | |
| 9 | Citadel Advisors LLC | 204,937 | -130,172 | 180,869,198.72 | 0.161 | 0.3312 | 03/31/2026 |
| 10 | Acadian Asset Management LLC | 0 | -117,887 | 0 | 0 | 0 |
Data provided by FactSet Research Systems Inc.