| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Ikarian Capital LLC | 211,538 | 0 | 888,459.6 | 0.1461 | 25.2138 | 03/31/2026 |
| 2 | Dauntless Investment Group LLC | 196,592 | 196,592 | 825,686.4 | 2.3486 | 23.4324 | 03/31/2026 |
| 3 | Millennium Management LLC | 110,011 | 55,680 | 462,046.2 | 0.0003 | 13.1125 | 05/26/2026 |
| 4 | Adar1 Capital Management LLC | 102,883 | 102,883 | 432,108.6 | 0.0259 | 12.2629 | 03/31/2026 |
| 5 | Summittx Capital LP | 100,300 | 100,300 | 421,260 | 0.0121 | 11.955 | 03/31/2026 |
| 6 | Velan Capital Investment Management LP | 84,849 | 84,849 | 356,365.8 | 0.2425 | 10.1134 | 03/31/2026 |
| 7 | Woodline Partners LP | 79,582 | 79,582 | 334,244.4 | 0.0011 | 9.4856 | 03/31/2026 |
| 8 | abrdn, Inc. | 75,000 | 75,000 | 315,000 | 0.0028 | 8.9395 | 04/01/2026 |
| 9 | Soleus Capital Management LP (Investment Management) | 72,730 | 72,730 | 305,466 | 0.0107 | 8.6689 | 03/31/2026 |
| 10 | Centiva Capital LP | 60,000 | 60,000 | 252,000 | 0.0107 | 7.1516 | 03/31/2026 |
| 11 | Boothbay Fund Management LLC | 59,838 | 59,838 | 251,319.6 | 0.0053 | 7.1323 | 03/31/2026 |
| 12 | Stonepine Capital Management LLC | 53,460 | 53,460 | 224,532 | 0.1021 | 6.3721 | 03/31/2026 |
| 13 | AIGH Capital Management LLC | 51,000 | 51,000 | 214,200 | 0.0244 | 6.0788 | 03/31/2026 |
| 14 | Citadel Advisors LLC | 32,519 | 32,519 | 136,579.8 | 0.0001 | 3.876 | 03/31/2026 |
| 15 | Birchview Capital LP | 20,000 | 20,000 | 84,000 | 0.0548 | 2.3839 | 03/31/2026 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | abrdn World Healthcare Fund | 40,400 | 16,696 | 169,680 | 0.03 | 4.8154 | 04/30/2026 |
| 2 | abrdn Life Sciences Investors | 34,600 | 34,600 | 145,320 | 0.025 | 4.1241 | 03/31/2026 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Dauntless Investment Group LLC | 196,592 | 196,592 | 825,686.4 | 2.3486 | 23.4324 | 03/31/2026 |
| 2 | Adar1 Capital Management LLC | 102,883 | 102,883 | 432,108.6 | 0.0259 | 12.2629 | 03/31/2026 |
| 3 | Summittx Capital LP | 100,300 | 100,300 | 421,260 | 0.0121 | 11.955 | 03/31/2026 |
| 4 | Velan Capital Investment Management LP | 84,849 | 84,849 | 356,365.8 | 0.2425 | 10.1134 | 03/31/2026 |
| 5 | Woodline Partners LP | 79,582 | 79,582 | 334,244.4 | 0.0011 | 9.4856 | 03/31/2026 |
| 6 | abrdn, Inc. | 75,000 | 75,000 | 315,000 | 0.0028 | 8.9395 | 04/01/2026 |
| 7 | Soleus Capital Management LP (Investment Management) | 72,730 | 72,730 | 305,466 | 0.0107 | 8.6689 | 03/31/2026 |
| 8 | Centiva Capital LP | 60,000 | 60,000 | 252,000 | 0.0107 | 7.1516 | 03/31/2026 |
| 9 | Boothbay Fund Management LLC | 59,838 | 59,838 | 251,319.6 | 0.0053 | 7.1323 | 03/31/2026 |
| 10 | Millennium Management LLC | 110,011 | 55,680 | 462,046.2 | 0.0003 | 13.1125 | 05/26/2026 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Resolute Capital Asset Partners LLC | 0 | -50,000 | 0 | 0 | 0 |
Data provided by FactSet Research Systems Inc.