| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Dauntless Investment Group LLC | 214,987 | 18,395 | 870,697.35 | 1.5866 | 10.7043 | 06/30/2026 |
| 2 | Ikarian Capital LLC | 211,538 | 0 | 856,728.9 | 0.1614 | 10.5326 | 09/30/2026 |
| 3 | Stonepine Capital Management LLC | 199,486 | 146,026 | 807,918.3 | 0.3505 | 9.9325 | 06/30/2026 |
| 4 | Millennium Management LLC | 112,323 | 36,076 | 454,908.15 | 0.0003 | 5.5926 | 06/30/2026 |
| 5 | Adar1 Capital Management LLC | 102,883 | 0 | 416,676.15 | 0.0227 | 5.1226 | 03/31/2026 |
| 6 | Summittx Capital LP | 100,300 | 0 | 406,215 | 0.0114 | 4.994 | 06/30/2026 |
| 7 | Woodline Partners LP | 76,446 | -3,136 | 309,606.3 | 0.001 | 3.8063 | 06/30/2026 |
| 8 | abrdn, Inc. | 75,000 | 0 | 303,750 | 0.0028 | 3.7343 | 06/30/2026 |
| 9 | Soleus Capital Management LP (Investment Management) | 72,730 | 0 | 294,556.5 | 0.011 | 3.6213 | 06/30/2026 |
| 10 | AIGH Capital Management LLC | 70,000 | 19,000 | 283,500 | 0.0322 | 3.4853 | 06/30/2026 |
| 11 | Boothbay Fund Management LLC | 59,838 | 0 | 242,343.9 | 0.005 | 2.9794 | 06/30/2026 |
| 12 | Velan Capital Investment Management LP | 32,372 | -52,477 | 131,106.6 | 0.1322 | 1.6118 | 06/30/2026 |
| 13 | Barclays Bank Plc (Private Banking) | 21,469 | 20,169 | 86,949.45 | 0 | 1.069 | 06/30/2026 |
| 14 | Birchview Capital LP | 20,000 | 0 | 81,000 | 0.0502 | 0.9958 | 06/30/2026 |
| 15 | XTX Markets LLC | 15,006 | 15,006 | 60,774.3 | 0.0008 | 0.7472 | 06/30/2026 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | abrdn Life Sciences Investors | 34,600 | 0 | 140,130 | 0.0247 | 1.7227 | 06/30/2026 |
| 2 | Abante Quant Value Small Caps | 10,491 | 10,491 | 42,488.55 | 0.2388 | 0.5224 | 06/30/2026 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Stonepine Capital Management LLC | 199,486 | 146,026 | 807,918.3 | 0.3505 | 9.9325 | 06/30/2026 |
| 2 | Millennium Management LLC | 112,323 | 36,076 | 454,908.15 | 0.0003 | 5.5926 | 06/30/2026 |
| 3 | Barclays Bank Plc (Private Banking) | 21,469 | 20,169 | 86,949.45 | 0 | 1.069 | 06/30/2026 |
| 4 | AIGH Capital Management LLC | 70,000 | 19,000 | 283,500 | 0.0322 | 3.4853 | 06/30/2026 |
| 5 | Dauntless Investment Group LLC | 214,987 | 18,395 | 870,697.35 | 1.5866 | 10.7043 | 06/30/2026 |
| 6 | XTX Markets LLC | 15,006 | 15,006 | 60,774.3 | 0.0008 | 0.7472 | 06/30/2026 |
| 7 | Abante Asesores Gestion SGIIC SA | 10,491 | 10,491 | 42,488.55 | 0.0031 | 0.5224 | 06/30/2026 |
| 8 | UBS Securities LLC | 6,772 | 4,260 | 27,426.6 | 0 | 0.3372 | 06/30/2026 |
| 9 | Morgan Stanley Smith Barney LLC (Investment Management) | 8,000 | 4,000 | 32,400 | 0 | 0.3983 | 06/30/2026 |
| 10 | GAMMA Investing LLC | 3,116 | 1,396 | 12,619.8 | 0.0004 | 0.1551 | 09/30/2026 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Centiva Capital LP | 0 | -60,000 | 0 | 0 | 0 | |
| 2 | Velan Capital Investment Management LP | 32,372 | -52,477 | 131,106.6 | 0.1322 | 1.6118 | 06/30/2026 |
| 3 | Citadel Advisors LLC | 0 | -32,519 | 0 | 0 | 0 | |
| 4 | Woodline Partners LP | 76,446 | -3,136 | 309,606.3 | 0.001 | 3.8063 | 06/30/2026 |
| 5 | RBC Dominion Securities, Inc. (Investment Management) | 0 | -11 | 0 | 0 | 0 |
Data provided by FactSet Research Systems Inc.