# Holder Name Position Position Change $ Market Value % Port % O/S Rpt Date
1 The B Group, Inc. 3,281,501 0 9,319,462.84 6.0888 4.5371 03/31/2026
2 Long Focus Capital Management LLC 2,744,098 -43,652 7,793,238.32 0.3074 3.7941 03/31/2026
3 UBS Asset Management (Americas) LLC 1,874,033 0 5,322,253.72 0.0026 2.5911 03/31/2026
4 UBS Asset Management Switzerland AG 1,304,587 0 3,705,027.08 0.001 1.8038 03/31/2026
5 BlackRock Fund Advisors 340,579 -5,295 967,244.36 0 0.4709 03/31/2026
6 Nomura Investment Management Business Trust 226,875 0 644,325 0.0008 0.3137 03/31/2026
7 LPL Financial LLC 84,345 -447 239,539.8 0.0001 0.1166 03/31/2026
8 Morgan Stanley & Co. International Plc 84,300 -537 239,412 0.002 0.1166 03/31/2026
9 Susquehanna Financial Group LLLP 54,435 2,012 154,595.4 0.0002 0.0753 03/31/2026
10 Citadel Securities LLC 44,315 -51,112 125,854.6 0.0003 0.0613 03/31/2026
11 Marshall Wace LLP 41,112 -137,361 116,758.08 0.0001 0.0568 03/31/2026
12 BNP Paribas Financial Markets SNC 41,000 -300 116,440 0.0001 0.0567 03/31/2026
13 UBS Securities LLC 27,145 -20,326 77,091.8 0 0.0375 03/31/2026
14 Hemenway Trust Co. LLC 24,000 0 68,160 0.0016 0.0332 03/31/2026
15 XTX Markets LLC 16,269 16,269 46,203.96 0.0007 0.0225 03/31/2026
# Holder Name Position Position Change $ Market Value % Port % O/S Rpt Date
1 UBS Lux Inv. SICAV 2 - Digital Health Equity Fund 1,304,587 0 3,705,027.08 0.6312 1.8038 03/31/2026
2 Nomura Healthcare Fund 226,875 0 644,325 0.0853 0.3137 05/29/2026
3 Galileo - Biotech Innovation Fund 226,071 0 642,041.64 1.5259 0.3126 12/31/2025
4 iShares Biotechnology ETF 223,114 -114,337 633,643.76 0.007 0.3085 06/30/2026
5 P & S Renditefonds 15,000 0 42,600 0.1422 0.0207 04/30/2026
# Holder Name Position Position Change $ Market Value % Port % O/S Rpt Date
1 XTX Markets LLC 16,269 16,269 46,203.96 0.0007 0.0225 03/31/2026
2 G1 Execution Services LLC 11,507 11,507 32,679.88 0.0018 0.0159 03/31/2026
3 Lido Advisors LLC 10,094 10,094 28,666.96 0.0001 0.014 03/31/2026
4 Susquehanna Financial Group LLLP 54,435 2,012 154,595.4 0.0002 0.0753 03/31/2026
5 RhumbLine Advisers LP 15,085 1,742 42,841.4 0 0.0209 03/31/2026
6 Tower Research Capital LLC 1,797 664 5,103.48 0.0001 0.0025 03/31/2026
7 Barclays Capital, Inc. 224 224 636.16 0 0.0003 03/31/2026
8 Morgan Stanley Smith Barney LLC (Investment Management) 2,426 90 6,889.84 0 0.0034 03/31/2026
9 Larson Financial Group LLC 75 75 213 0 0.0001 03/31/2026
10 Morgan Stanley & Co. LLC 50 47 142 0 0.0001 03/31/2026
# Holder Name Position Position Change $ Market Value % Port % O/S Rpt Date
1 Marshall Wace LLP 41,112 -137,361 116,758.08 0.0001 0.0568 03/31/2026
2 Citadel Securities LLC 44,315 -51,112 125,854.6 0.0003 0.0613 03/31/2026
3 Long Focus Capital Management LLC 2,744,098 -43,652 7,793,238.32 0.3074 3.7941 03/31/2026
4 Aperio Group LLC 944 -37,481 2,680.96 0 0.0013 03/31/2026
5 Point72 Asset Management LP 0 -27,314 0 0 0
6 UBS Securities LLC 27,145 -20,326 77,091.8 0 0.0375 03/31/2026
7 First Affirmative Financial Network LLC 0 -10,149 0 0 0
8 BlackRock Fund Advisors 340,579 -5,295 967,244.36 0 0.4709 03/31/2026
9 BofA Securities, Inc. 0 -3,437 0 0 0
10 Citigroup Global Markets, Inc. (Investment Management) 1 -2,557 2.84 0 0 03/31/2026

Data provided by FactSet Research Systems Inc.