| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | HHLR Advisors Ltd. | 5,980,568 | 0 | 24,699,745.84 | 0.192 | 7.3941 | 06/30/2025 |
| 2 | Candriam Belgium SA | 1,132,563 | 1,132,563 | 4,677,485.19 | 0.0127 | 1.4003 | 06/30/2025 |
| 3 | SG Americas Securities LLC | 876,353 | 54,312 | 3,619,337.89 | 0.0142 | 1.0835 | 06/30/2025 |
| 4 | Abaris Investment Management AG | 282,000 | 0 | 1,164,660 | 1.6815 | 0.3487 | 12/31/2024 |
| 5 | Two Sigma Advisers LP | 209,383 | -153,817 | 864,751.79 | 0.0016 | 0.2589 | 06/30/2025 |
| 6 | UBS Securities LLC | 184,845 | -133,701 | 763,409.85 | 0.0003 | 0.2285 | 06/30/2025 |
| 7 | abrdn, Inc. | 136,471 | -26,109 | 563,625.23 | 0.0054 | 0.1687 | 06/30/2025 |
| 8 | BNP Paribas Financial Markets | 122,405 | 1,496 | 505,532.65 | 0.0004 | 0.1513 | 06/30/2025 |
| 9 | Two Sigma Investments LP | 113,262 | -97,104 | 467,772.06 | 0.0008 | 0.14 | 06/30/2025 |
| 10 | Ariose Capital Management Ltd. | 96,455 | 96,455 | 398,359.15 | 0.2206 | 0.1193 | 06/30/2025 |
| 11 | Saint Olive Gestion SNC | 80,000 | 0 | 330,400 | 0.0742 | 0.0989 | 12/29/2023 |
| 12 | Alberta Investment Management Corp. | 74,723 | 0 | 308,605.99 | 0.0031 | 0.0924 | 06/30/2025 |
| 13 | Renaissance Technologies LLC | 63,700 | -100 | 263,081 | 0.0003 | 0.0788 | 06/30/2025 |
| 14 | Morgan Stanley & Co. LLC | 58,295 | 23,478 | 240,758.35 | 0.0001 | 0.0721 | 06/30/2025 |
| 15 | Geode Capital Management LLC | 54,562 | 32,525 | 225,341.06 | 0 | 0.0675 | 06/30/2025 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | SPDR Portfolio Emerging Markets ETF | 271,000 | 271,000 | 1,119,230 | 0.0077 | 0.3351 | 09/30/2025 |
| 2 | Abaris Emerging Markets Equity | 124,000 | 0 | 512,120 | 3.9237 | 0.1533 | 04/30/2024 |
| 3 | ALPS Barrons 400 ETF | 111,490 | 111,490 | 460,453.7 | 0.2519 | 0.1378 | 09/30/2025 |
| 4 | Abaris Biotechnology Opportunities | 100,000 | 0 | 413,000 | 1.8792 | 0.1236 | 12/31/2024 |
| 5 | BSO Bio Sante | 80,000 | 0 | 330,400 | 0.1207 | 0.0989 | 12/29/2023 |
| 6 | Abaris Defensive Equity | 58,000 | 0 | 239,540 | 0.9353 | 0.0717 | 10/31/2023 |
| 7 | Fidelity Nasdaq Composite Index Fund | 54,562 | 32,525 | 225,341.06 | 0.001 | 0.0675 | 08/31/2025 |
| 8 | SPDR S&P Emerging Markets Small Cap ETF | 52,900 | 52,900 | 218,477 | 0.0298 | 0.0654 | 09/30/2025 |
| 9 | abrdn Healthcare Opportunities Fund | 43,738 | 0 | 180,637.94 | 0.0215 | 0.0541 | 08/31/2025 |
| 10 | DFA Emerging Markets Social Core Equity Portfolio | 18,909 | 0 | 78,094.17 | 0.0041 | 0.0234 | 07/31/2025 |
| 11 | DFA Emerging Markets Core Equity 2 Portfolio | 16,217 | 16,217 | 66,976.21 | 0.0002 | 0.02 | 07/31/2025 |
| 12 | Dimensional Funds II Plc - Emerging Markets Targeted Value Fd. | 14,503 | -518 | 59,897.39 | 0.0089 | 0.0179 | 05/31/2025 |
| 13 | SPDR S&P China ETF | 13,500 | 13,500 | 55,755 | 0.0109 | 0.0167 | 09/30/2025 |
| 14 | DFA Emerging Markets Sustainability Core 1 Portfolio | 9,306 | 0 | 38,433.78 | 0.003 | 0.0115 | 07/31/2025 |
| 15 | ActivePassive International Equity ETF | 8,158 | 8,158 | 33,692.54 | 0.0036 | 0.0101 | 09/30/2025 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Candriam Belgium SA | 1,132,563 | 1,132,563 | 4,677,485.19 | 0.0127 | 1.4003 | 06/30/2025 |
| 2 | Ariose Capital Management Ltd. | 96,455 | 96,455 | 398,359.15 | 0.2206 | 0.1193 | 06/30/2025 |
| 3 | SG Americas Securities LLC | 876,353 | 54,312 | 3,619,337.89 | 0.0142 | 1.0835 | 06/30/2025 |
| 4 | Susquehanna Financial Group LLLP | 37,537 | 37,537 | 155,027.81 | 0.0002 | 0.0464 | 06/30/2025 |
| 5 | CreativeOne Wealth LLC | 37,430 | 37,430 | 154,585.9 | 0.0038 | 0.0463 | 06/30/2025 |
| 6 | Geode Capital Management LLC | 54,562 | 32,525 | 225,341.06 | 0 | 0.0675 | 06/30/2025 |
| 7 | Connor, Clark & Lunn Investment Management Ltd. | 27,800 | 27,800 | 114,814 | 0.0003 | 0.0344 | 06/30/2025 |
| 8 | Morgan Stanley & Co. LLC | 58,295 | 23,478 | 240,758.35 | 0.0001 | 0.0721 | 06/30/2025 |
| 9 | Two Sigma Securities LLC | 12,821 | 12,821 | 52,950.73 | 0.0061 | 0.0159 | 06/30/2025 |
| 10 | Baxter Bros., Inc. | 10,000 | 10,000 | 41,300 | 0.0049 | 0.0124 | 06/30/2025 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Stonepine Capital Management LLC | 0 | -483,647 | 0 | 0 | 0 | |
| 2 | Two Sigma Advisers LP | 209,383 | -153,817 | 864,751.79 | 0.0016 | 0.2589 | 06/30/2025 |
| 3 | UBS Securities LLC | 184,845 | -133,701 | 763,409.85 | 0.0003 | 0.2285 | 06/30/2025 |
| 4 | Two Sigma Investments LP | 113,262 | -97,104 | 467,772.06 | 0.0008 | 0.14 | 06/30/2025 |
| 5 | Ground Swell Capital LLC | 0 | -63,730 | 0 | 0 | 0 | |
| 6 | Millennium Management LLC | 0 | -61,478 | 0 | 0 | 0 | |
| 7 | HBK Sorce Advisory LLC | 0 | -46,060 | 0 | 0 | 0 | |
| 8 | abrdn, Inc. | 136,471 | -26,109 | 563,625.23 | 0.0054 | 0.1687 | 06/30/2025 |
| 9 | JPMorgan Securities LLC (Investment Management) | 0 | -5,000 | 0 | 0 | 0 | |
| 10 | Simplex Trading LLC | 0 | -3,229 | 0 | 0 | 0 |
Data provided by FactSet Research Systems Inc.