| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Rubric Capital Management LP | 15,307,347 | 0 | 4,408,515.94 | 0.0456 | 9.59 | 03/31/2026 |
| 2 | EcoR1 Capital, LLC | 13,368,855 | 5,512,389 | 3,850,230.24 | 0.1312 | 8.3755 | 03/31/2026 |
| 3 | 683 Capital Management LLC | 12,000,000 | -3,025,000 | 3,456,000 | 0.2803 | 7.5179 | 03/31/2026 |
| 4 | BofA Securities, Inc. | 8,195,287 | 8,195,281 | 2,360,242.66 | 0.0033 | 5.1343 | 03/31/2026 |
| 5 | Defilade Capital Management LP | 7,558,756 | 7,558,756 | 2,176,921.73 | 0.2826 | 4.7355 | 03/31/2026 |
| 6 | Newtyn Management LLC | 7,079,056 | 6,854,434 | 2,038,768.13 | 0.1957 | 4.435 | 03/31/2026 |
| 7 | Millennium Management LLC | 3,559,103 | 3,475,457 | 1,025,021.66 | 0.0007 | 2.2298 | 03/31/2026 |
| 8 | Tejara Capital Ltd. | 2,037,520 | -122,161 | 586,805.76 | 0.1581 | 1.2765 | 03/31/2026 |
| 9 | UBS Securities LLC | 1,481,151 | 1,255,693 | 426,571.49 | 0.0002 | 0.9279 | 03/31/2026 |
| 10 | TruValue Asset Management Co. Ltd. | 992,095 | 0 | 285,723.36 | 0.0133 | 0.6215 | 12/31/2025 |
| 11 | Wealthspire Advisors LLC | 796,036 | 796,036 | 229,258.37 | 0.0016 | 0.4987 | 03/31/2026 |
| 12 | Marshall Wace LLP | 686,987 | 686,987 | 197,852.26 | 0.0002 | 0.4304 | 03/31/2026 |
| 13 | Group One Trading LLC | 335,827 | -105,809 | 96,718.18 | 0.0029 | 0.2104 | 03/31/2026 |
| 14 | Rangeley Capital LLC | 329,200 | -34,800 | 94,809.6 | 0.0777 | 0.2062 | 03/31/2026 |
| 15 | David M. Knott Partnership | 300,337 | 0 | 86,497.06 | 0.0443 | 0.1882 | 03/31/2026 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | CSOP Glb Pharmaceutical and Biological Stock Initiation QDII | 992,095 | 0 | 285,723.36 | 0.1878 | 0.6215 | 12/31/2025 |
| 2 | State Street SPDR S&P International Small Cap ETF | 134,772 | 4,129 | 38,814.34 | 0.0045 | 0.0844 | 06/30/2026 |
| 3 | Fidelity Nasdaq Composite Index Fund | 92,534 | 0 | 26,649.79 | 0.0001 | 0.058 | 05/31/2026 |
| 4 | Blackstone Alternative Multi Strategy Fund | 1,200 | -3,400 | 345.6 | 0 | 0.0008 | 03/31/2026 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | BofA Securities, Inc. | 8,195,287 | 8,195,281 | 2,360,242.66 | 0.0033 | 5.1343 | 03/31/2026 |
| 2 | Defilade Capital Management LP | 7,558,756 | 7,558,756 | 2,176,921.73 | 0.2826 | 4.7355 | 03/31/2026 |
| 3 | Newtyn Management LLC | 7,079,056 | 6,854,434 | 2,038,768.13 | 0.1957 | 4.435 | 03/31/2026 |
| 4 | EcoR1 Capital, LLC | 13,368,855 | 5,512,389 | 3,850,230.24 | 0.1312 | 8.3755 | 03/31/2026 |
| 5 | Millennium Management LLC | 3,559,103 | 3,475,457 | 1,025,021.66 | 0.0007 | 2.2298 | 03/31/2026 |
| 6 | UBS Securities LLC | 1,481,151 | 1,255,693 | 426,571.49 | 0.0002 | 0.9279 | 03/31/2026 |
| 7 | Wealthspire Advisors LLC | 796,036 | 796,036 | 229,258.37 | 0.0016 | 0.4987 | 03/31/2026 |
| 8 | Marshall Wace LLP | 686,987 | 686,987 | 197,852.26 | 0.0002 | 0.4304 | 03/31/2026 |
| 9 | Susquehanna Financial Group LLLP | 166,309 | 166,309 | 47,896.99 | 0.0001 | 0.1042 | 03/31/2026 |
| 10 | Acadian Asset Management LLC | 209,084 | 147,649 | 60,216.19 | 0.0001 | 0.131 | 03/31/2026 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Schonfeld Strategic Advisors LLC | 0 | -6,090,381 | 0 | 0 | 0 | |
| 2 | 683 Capital Management LLC | 12,000,000 | -3,025,000 | 3,456,000 | 0.2803 | 7.5179 | 03/31/2026 |
| 3 | Logos Global Management LP | 0 | -1,850,000 | 0 | 0 | 0 | |
| 4 | UBS Asset Management Switzerland AG | 0 | -1,763,666 | 0 | 0 | 0 | |
| 5 | Adage Capital Management LP | 0 | -1,700,756 | 0 | 0 | 0 | |
| 6 | Monaco Asset Management SAM | 0 | -1,585,214 | 0 | 0 | 0 | |
| 7 | UBS Switzerland AG (Investment Management) | 3,065 | -1,318,583 | 882.72 | 0 | 0.0019 | 03/31/2026 |
| 8 | Balyasny Asset Management LP | 0 | -1,280,275 | 0 | 0 | 0 | |
| 9 | Morgan Stanley & Co. LLC | 14,006 | -1,256,760 | 4,033.73 | 0 | 0.0088 | 03/31/2026 |
| 10 | Simplex Trading LLC | 0 | -419,477 | 0 | 0 | 0 |
Data provided by FactSet Research Systems Inc.