| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Legal & General Investment Management Ltd. | 679,023 | 679,023 | 11,482,278.93 | 0.0039 | 0.5263 | 12/31/2025 |
| 2 | BlackRock Fund Advisors | 502,353 | 3,357 | 8,494,789.23 | 0.0002 | 0.3893 | 12/31/2025 |
| 3 | Susquehanna Financial Group LLLP | 429,844 | 195,257 | 7,268,662.04 | 0.0102 | 0.3331 | 12/31/2025 |
| 4 | Morgan Stanley & Co. International Plc | 413,500 | 99,978 | 6,992,285 | 0.0643 | 0.3205 | 12/31/2025 |
| 5 | Goldman Sachs & Co. LLC (Private Banking) | 395,850 | -19,615 | 6,693,823.5 | 0.0029 | 0.3068 | 12/31/2025 |
| 6 | Morgan Stanley & Co. LLC | 171,759 | -7,676 | 2,904,444.69 | 0.001 | 0.1331 | 12/31/2025 |
| 7 | Jane Street Capital LLC | 167,380 | 167,380 | 2,830,395.8 | 0.0032 | 0.1297 | 12/31/2025 |
| 8 | Arax Advisory Partners | 166,482 | 166,482 | 2,815,210.62 | 0.08 | 0.129 | 12/31/2025 |
| 9 | Aperio Group LLC | 140,507 | 5,340 | 2,375,973.37 | 0.0017 | 0.1089 | 12/31/2025 |
| 10 | Citadel Securities LLC | 122,868 | 48,232 | 2,077,697.88 | 0.0043 | 0.0952 | 12/31/2025 |
| 11 | Penbrook Management LLC | 87,575 | -100 | 1,480,893.25 | 1.0359 | 0.0679 | 12/31/2025 |
| 12 | Two Sigma Investments LP | 57,561 | 24,348 | 973,356.51 | 0.0014 | 0.0446 | 12/31/2025 |
| 13 | Prosperity Wealth Management, Inc. | 49,950 | -150 | 844,654.5 | 0.2979 | 0.0387 | 09/30/2025 |
| 14 | LPL Financial LLC | 48,747 | -1,300 | 824,311.77 | 0.0002 | 0.0378 | 12/31/2025 |
| 15 | Rialto Wealth Management LLC | 46,500 | 46,500 | 786,315 | 0.1809 | 0.036 | 12/31/2025 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | iShares Biotechnology ETF | 507,996 | 13,781 | 8,590,212.36 | 0.0992 | 0.3937 | 01/30/2026 |
| 2 | Legal & General UCITS ETF Plc - Pharma Breakthrough | 35,139 | 35,139 | 594,200.49 | 2.9149 | 0.0272 | 01/30/2026 |
| 3 | iShares IV Plc - NASDAQ US Biotechnology UCITS ETF | 34,832 | 8,057 | 589,009.12 | 0.0604 | 0.027 | 01/30/2026 |
| 4 | Fidelity Nasdaq Composite Index Fund | 30,737 | 12,417 | 519,762.67 | 0.0023 | 0.0238 | 12/31/2025 |
| 5 | Invesco Markets Plc - NASDAQ Biotech UCITS ETF | 16,127 | 2,814 | 272,707.57 | 0.0616 | 0.0125 | 01/30/2026 |
| 6 | Polen US Small Company Growth Fund | 10,525 | 10,525 | 177,977.75 | 0.4029 | 0.0082 | 12/31/2025 |
| 7 | China Universal Nasdaq Biotechnology Index ETF | 9,124 | 0 | 154,286.84 | 0.063 | 0.0071 | 06/30/2025 |
| 8 | ActivePassive International Equity ETF | 3,923 | -1,047 | 66,337.93 | 0.0065 | 0.003 | 01/30/2026 |
| 9 | Mirae Asset Tiger NASDAQ Bio ETF | 2,867 | 760 | 48,480.97 | 0.0632 | 0.0022 | 01/30/2026 |
| 10 | Invesco Nasdaq Biotechnology ETF | 2,710 | 1,093 | 45,826.1 | 0.0611 | 0.0021 | 01/30/2026 |
| 11 | ProShares Ultra NASDAQ Biotechnology | 2,296 | 623 | 38,825.36 | 0.0436 | 0.0018 | 01/30/2026 |
| 12 | Xtrackers IE Plc - MSCI Genomic Healthcare Innov UCITS ETF | 1,168 | -384 | 19,750.88 | 0.2984 | 0.0009 | 01/30/2026 |
| 13 | GF Nasdaq Biotechnology Index Fund | 817 | 0 | 13,815.47 | 0.0384 | 0.0006 | 06/30/2025 |
| 14 | Capital Nasdaq Biotechnology Index ETF | 135 | 0 | 2,282.85 | 0.0233 | 0.0001 | 01/30/2026 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Legal & General Investment Management Ltd. | 679,023 | 679,023 | 11,482,278.93 | 0.0039 | 0.5263 | 12/31/2025 |
| 2 | Susquehanna Financial Group LLLP | 429,844 | 195,257 | 7,268,662.04 | 0.0102 | 0.3331 | 12/31/2025 |
| 3 | Jane Street Capital LLC | 167,380 | 167,380 | 2,830,395.8 | 0.0032 | 0.1297 | 12/31/2025 |
| 4 | Arax Advisory Partners | 166,482 | 166,482 | 2,815,210.62 | 0.08 | 0.129 | 12/31/2025 |
| 5 | Morgan Stanley & Co. International Plc | 413,500 | 99,978 | 6,992,285 | 0.0643 | 0.3205 | 12/31/2025 |
| 6 | Citadel Securities LLC | 122,868 | 48,232 | 2,077,697.88 | 0.0043 | 0.0952 | 12/31/2025 |
| 7 | Rialto Wealth Management LLC | 46,500 | 46,500 | 786,315 | 0.1809 | 0.036 | 12/31/2025 |
| 8 | Point72 Asset Management LP | 38,185 | 38,185 | 645,708.35 | 0.001 | 0.0296 | 12/31/2025 |
| 9 | UBS Europe SE | 28,622 | 28,622 | 483,998.02 | 0.0086 | 0.0222 | 12/31/2025 |
| 10 | Quadrature Capital Ltd. | 26,566 | 26,566 | 449,231.06 | 0.0044 | 0.0206 | 12/31/2025 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Summit X LLC | 0 | -199,295 | 0 | 0 | 0 | |
| 2 | UBS Securities LLC | 35,856 | -124,182 | 606,324.96 | 0.0002 | 0.0278 | 12/31/2025 |
| 3 | Marex Capital Markets, Inc. | 0 | -100,000 | 0 | 0 | 0 | |
| 4 | Group One Trading LLC | 0 | -90,902 | 0 | 0 | 0 | |
| 5 | RBC Dominion Securities, Inc. (Investment Management) | 21,439 | -63,961 | 362,533.49 | 0.0003 | 0.0166 | 12/31/2025 |
| 6 | Rockbridge Investment Management LLC | 0 | -49,150 | 0 | 0 | 0 | |
| 7 | Millennium Management LLC | 0 | -32,283 | 0 | 0 | 0 | |
| 8 | UBS Switzerland AG (Investment Management) | 2,237 | -31,712 | 37,827.67 | 0.0001 | 0.0017 | 12/31/2025 |
| 9 | Oasis Management (Hong Kong) LLC | 0 | -29,524 | 0 | 0 | 0 | |
| 10 | Verition Fund Management LLC | 0 | -28,844 | 0 | 0 | 0 |
Data provided by FactSet Research Systems Inc.