# Holder Name Position Position Change $ Market Value % Port % O/S Rpt Date
1 BlackRock Fund Advisors 500,585 -1,768 7,749,055.8 0.0001 0.3854 06/30/2026
2 Susquehanna Financial Group LLLP 457,744 27,900 7,085,877.12 0.0064 0.3525 06/30/2026
3 Morgan Stanley & Co. International Plc 413,500 0 6,400,980 0.0451 0.3184 06/30/2026
4 Goldman Sachs & Co. LLC (Private Banking) 395,612 -238 6,124,073.76 0.0015 0.3046 06/30/2026
5 Morgan Stanley & Co. LLC 291,504 119,745 4,512,481.92 0.0013 0.2244 06/30/2026
6 AXA Investment Managers UK Ltd. 259,700 259,700 4,020,156 0.0121 0.2 06/30/2026
7 Arax Advisory Partners LLC 168,022 1,540 2,600,980.56 0.0169 0.1294 06/30/2026
8 Aperio Group LLC 123,876 -16,631 1,917,600.48 0.0011 0.0954 06/30/2026
9 UBS Securities LLC 119,024 83,168 1,842,491.52 0.0007 0.0916 06/30/2026
10 Merrill Lynch International (Investment Management) 100,000 100,000 1,548,000 0.0056 0.077 06/30/2026
11 Penbrook Management LLC 87,075 -500 1,347,921 0.8599 0.067 06/30/2026
12 UBS Switzerland AG (Investment Management) 64,484 62,247 998,212.32 0.0015 0.0497 06/30/2026
13 M&G Investment Management Ltd. 59,100 59,100 914,868 0.001 0.0455 06/30/2026
14 Quadrature Capital Ltd. 53,126 26,560 822,390.48 0.0068 0.0409 06/30/2026
15 LPL Financial LLC 47,867 -880 740,981.16 0.0002 0.0369 06/30/2026
# Holder Name Position Position Change $ Market Value % Port % O/S Rpt Date
1 iShares Biotechnology ETF 524,483 10,331 8,118,996.84 0.0782 0.4038 08/31/2026
2 AXA Framlington Biotech Fund 259,700 259,700 4,020,156 0.8523 0.2 07/31/2026
3 M&G Investment Funds (3) - Recovery Fund 59,100 0 914,868 0.0658 0.0455 05/31/2026
4 iShares IV Plc - NASDAQ US Biotechnology UCITS ETF 42,888 7,586 663,906.24 0.0539 0.033 08/31/2026
5 Fidelity Nasdaq Composite Index Fund 33,747 3,010 522,403.56 0.0018 0.026 07/31/2026
6 Invesco Markets Plc - NASDAQ Biotech UCITS ETF 16,346 179 253,036.08 0.053 0.0126 08/31/2026
7 ActivePassive International Equity ETF 8,838 4,891 136,812.24 0.0119 0.0068 08/31/2026
8 China Universal Nasdaq Biotechnology Index ETF 8,319 327 128,778.12 0.0532 0.0064 06/30/2026
9 Invesco NASDAQ Future Gen 200 ETF 7,253 7,253 112,276.44 0.5067 0.0056 08/31/2026
10 Steward Values Enhanced International Fund 6,507 0 100,728.36 0.0291 0.005 07/31/2026
11 Invesco Nasdaq Biotechnology ETF 3,265 544 50,542.2 0.053 0.0025 08/31/2026
12 Mirae Asset Tiger NASDAQ Bio ETF 2,707 73 41,904.36 0.0551 0.0021 08/31/2026
13 ProShares Ultra NASDAQ Biotechnology 1,870 -394 28,947.6 0.0287 0.0014 08/31/2026
14 Xtrackers IE Plc - MSCI Genomic Healthcare Innov UCITS ETF 1,680 512 26,006.4 0.2185 0.0013 08/31/2026
15 GF Nasdaq Biotechnology Index Fund 964 0 14,922.72 0.0449 0.0007 12/31/2025
# Holder Name Position Position Change $ Market Value % Port % O/S Rpt Date
1 AXA Investment Managers UK Ltd. 259,700 259,700 4,020,156 0.0121 0.2 06/30/2026
2 Morgan Stanley & Co. LLC 291,504 119,745 4,512,481.92 0.0013 0.2244 06/30/2026
3 Merrill Lynch International (Investment Management) 100,000 100,000 1,548,000 0.0056 0.077 06/30/2026
4 UBS Securities LLC 119,024 83,168 1,842,491.52 0.0007 0.0916 06/30/2026
5 UBS Switzerland AG (Investment Management) 64,484 62,247 998,212.32 0.0015 0.0497 06/30/2026
6 M&G Investment Management Ltd. 59,100 59,100 914,868 0.001 0.0455 06/30/2026
7 Group One Trading LLC 44,030 44,030 681,584.4 0.02 0.0339 06/30/2026
8 Susquehanna Financial Group LLLP 457,744 27,900 7,085,877.12 0.0064 0.3525 06/30/2026
9 Quadrature Capital Ltd. 53,126 26,560 822,390.48 0.0068 0.0409 06/30/2026
10 RBC Dominion Securities, Inc. (Investment Management) 44,003 22,564 681,166.44 0.0006 0.0339 06/30/2026
# Holder Name Position Position Change $ Market Value % Port % O/S Rpt Date
1 Legal & General Investment Management Ltd. 0 -679,023 0 0 0
2 Jane Street Capital LLC 33,152 -134,228 513,192.96 0.0003 0.0255 06/30/2026
3 Citadel Securities LLC 0 -122,868 0 0 0
4 Prosperity Wealth Management, Inc. 0 -50,900 0 0 0
5 Point72 Asset Management LP 0 -38,185 0 0 0
6 UBS Europe SE 0 -28,622 0 0 0
7 Polen Capital Management LLC 0 -23,005 0 0 0
8 49 Wealth Management LLC 0 -18,279 0 0 0
9 Opal Capital LLC 0 -18,279 0 0 0
10 Aperio Group LLC 123,876 -16,631 1,917,600.48 0.0011 0.0954 06/30/2026

Data provided by FactSet Research Systems Inc.