| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | BlackRock Fund Advisors | 498,996 | -66,891 | 8,532,831.6 | 0.0002 | 0.3927 | 06/30/2025 |
| 2 | Goldman Sachs & Co. LLC (Private Banking) | 415,465 | 158,322 | 7,104,451.5 | 0.0029 | 0.327 | 06/30/2025 |
| 3 | Morgan Stanley & Co. International Plc | 313,522 | 0 | 5,361,226.2 | 0.0537 | 0.2468 | 06/30/2025 |
| 4 | Susquehanna Financial Group LLLP | 234,587 | -26,354 | 4,011,437.7 | 0.0057 | 0.1846 | 06/30/2025 |
| 5 | Summit X LLC | 199,295 | 1,132 | 3,407,944.5 | 0.5831 | 0.1569 | 06/30/2025 |
| 6 | Morgan Stanley & Co. LLC | 179,435 | -44,824 | 3,068,338.5 | 0.001 | 0.1412 | 06/30/2025 |
| 7 | UBS Securities LLC | 160,038 | 22,703 | 2,736,649.8 | 0.0011 | 0.126 | 06/30/2025 |
| 8 | Aperio Group LLC | 135,167 | 2,678 | 2,311,355.7 | 0.0018 | 0.1064 | 06/30/2025 |
| 9 | Marex Capital Markets, Inc. | 100,000 | 100,000 | 1,710,000 | 0.0552 | 0.0787 | 06/30/2025 |
| 10 | Group One Trading LLC | 90,902 | -60,329 | 1,554,424.2 | 0.0408 | 0.0715 | 06/30/2025 |
| 11 | Penbrook Management LLC | 87,675 | 0 | 1,499,242.5 | 1.0553 | 0.069 | 09/30/2025 |
| 12 | RBC Dominion Securities, Inc. (Investment Management) | 85,400 | 75,400 | 1,460,340 | 0.0011 | 0.0672 | 06/30/2025 |
| 13 | Citadel Securities LLC | 74,636 | -412,157 | 1,276,275.6 | 0.0038 | 0.0587 | 06/30/2025 |
| 14 | Prosperity Wealth Management, Inc. | 50,100 | 1,400 | 856,710 | 0.291 | 0.0394 | 06/30/2025 |
| 15 | LPL Financial LLC | 50,047 | 10,040 | 855,803.7 | 0.0003 | 0.0394 | 06/30/2025 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | iShares Biotechnology ETF | 385,063 | -187,124 | 6,584,577.3 | 0.1035 | 0.3031 | 09/30/2025 |
| 2 | Legal & General UCITS ETF Plc - Pharma Breakthrough | 32,278 | 32,278 | 551,953.8 | 3.0669 | 0.0254 | 09/30/2025 |
| 3 | iShares IV Plc - NASDAQ US Biotechnology UCITS ETF | 26,860 | 10,134 | 459,306 | 0.0709 | 0.0211 | 09/30/2025 |
| 4 | Fidelity Nasdaq Composite Index Fund | 18,320 | 75 | 313,272 | 0.0014 | 0.0144 | 08/31/2025 |
| 5 | Invesco Markets Plc - NASDAQ Biotech UCITS ETF | 15,353 | 5,614 | 262,536.3 | 0.0709 | 0.0121 | 09/30/2025 |
| 6 | China Universal Nasdaq Biotechnology Index ETF | 9,124 | 2,348 | 156,020.4 | 0.0725 | 0.0072 | 06/30/2025 |
| 7 | ActivePassive International Equity ETF | 4,272 | -4,202 | 73,051.2 | 0.0078 | 0.0034 | 09/30/2025 |
| 8 | Mirae Asset Tiger NASDAQ Bio ETF | 2,044 | 795 | 34,952.4 | 0.0707 | 0.0016 | 09/30/2025 |
| 9 | ProShares Ultra NASDAQ Biotechnology | 1,682 | 148 | 28,762.2 | 0.0523 | 0.0013 | 09/30/2025 |
| 10 | Invesco Nasdaq Biotechnology ETF | 1,672 | 250 | 28,591.2 | 0.0709 | 0.0013 | 09/30/2025 |
| 11 | Xtrackers IE Plc - MSCI Genomic Healthcare Innov UCITS ETF | 1,456 | 1,456 | 24,897.6 | 0.3492 | 0.0011 | 09/30/2025 |
| 12 | GF Nasdaq Biotechnology Index Fund | 817 | 146 | 13,970.7 | 0.044 | 0.0006 | 06/30/2025 |
| 13 | DFA International Core Equity 2 Portfolio | 796 | 0 | 13,611.6 | 0 | 0.0006 | 07/31/2025 |
| 14 | Capital Nasdaq Biotechnology Index ETF | 135 | 0 | 2,308.5 | 0.0258 | 0.0001 | 09/30/2025 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Goldman Sachs & Co. LLC (Private Banking) | 415,465 | 158,322 | 7,104,451.5 | 0.0029 | 0.327 | 06/30/2025 |
| 2 | Marex Capital Markets, Inc. | 100,000 | 100,000 | 1,710,000 | 0.0552 | 0.0787 | 06/30/2025 |
| 3 | RBC Dominion Securities, Inc. (Investment Management) | 85,400 | 75,400 | 1,460,340 | 0.0011 | 0.0672 | 06/30/2025 |
| 4 | Two Sigma Investments LP | 33,213 | 33,213 | 567,942.3 | 0.001 | 0.0261 | 06/30/2025 |
| 5 | UBS Switzerland AG (Investment Management) | 33,949 | 30,789 | 580,527.9 | 0.0013 | 0.0267 | 06/30/2025 |
| 6 | Verition Fund Management LLC | 28,844 | 28,844 | 493,232.4 | 0.0025 | 0.0227 | 06/30/2025 |
| 7 | UBS Securities LLC | 160,038 | 22,703 | 2,736,649.8 | 0.0011 | 0.126 | 06/30/2025 |
| 8 | 49 Wealth Management LLC | 17,829 | 17,829 | 304,875.9 | 0.031 | 0.014 | 06/30/2025 |
| 9 | Millennium Management LLC | 32,283 | 15,161 | 552,039.3 | 0.0005 | 0.0254 | 06/30/2025 |
| 10 | AQR Capital Management LLC | 13,932 | 13,932 | 238,237.2 | 0.0002 | 0.011 | 06/30/2025 |
| # | Holder Name | Position | Position Change | $ Market Value | % Port | % O/S | Rpt Date |
|---|---|---|---|---|---|---|---|
| 1 | Citadel Securities LLC | 74,636 | -412,157 | 1,276,275.6 | 0.0038 | 0.0587 | 06/30/2025 |
| 2 | TD Securities (USA) LLC | 0 | -150,000 | 0 | 0 | 0 | |
| 3 | BlackRock Fund Advisors | 498,996 | -66,891 | 8,532,831.6 | 0.0002 | 0.3927 | 06/30/2025 |
| 4 | Group One Trading LLC | 90,902 | -60,329 | 1,554,424.2 | 0.0408 | 0.0715 | 06/30/2025 |
| 5 | Cubist Systematic Strategies LLC | 12,204 | -59,687 | 208,688.4 | 0.0021 | 0.0096 | 06/30/2025 |
| 6 | Jane Street Capital LLC | 0 | -48,601 | 0 | 0 | 0 | |
| 7 | Morgan Stanley & Co. LLC | 179,435 | -44,824 | 3,068,338.5 | 0.001 | 0.1412 | 06/30/2025 |
| 8 | Marshall Wace LLP | 40,710 | -30,941 | 696,141 | 0.0008 | 0.032 | 06/30/2025 |
| 9 | XY Capital Ltd. | 0 | -27,755 | 0 | 0 | 0 | |
| 10 | Susquehanna Financial Group LLLP | 234,587 | -26,354 | 4,011,437.7 | 0.0057 | 0.1846 | 06/30/2025 |
Data provided by FactSet Research Systems Inc.